(9) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia. Cisplatin-etoposide regimen related toxicity is high, weekly regimens have been investigating. Joint and equal in authority; taking cognizance of similar questions; operating on the same objects; as, the concurrent jurisdiction of courts. (11) The results support Kuiper and colleagues' distinction between concomitant and vulnerability schemas, and help to clarify differences between cognitions that are symptoms or correlates of depression and those that may play a causal role under certain conditions. The optimal chemotherapy regimen for concurrent chemoradiation in locally advanced non-small cell lung cancer (NSCLC) remains unclear. Concomitant is a synonym for concurrent in simultaneous topic. (1) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells. * 1970 , Alvin Toffler, Future Shock'', ''Bantam Books , pg. As adjectives the difference between contemporaneous and concurrent is that contemporaneous is existing or created in the same period of time while concurrent is happening at the same time; simultaneous. However, around one-third of the patients cannot complete cisplatin because of toxicity. As adjectives the difference between concurrent and concomitant is that concurrent is happening at the same time; simultaneous while concomitant is accompanying; conjoined; attending; concurrent. The other arm (arm B) received concomitant chemoradiotherapy consisting of concomitant EBRT (50.4 Gy in 28 fractions over 5.6 weeks, given five fractions per week) and two 5-day cycles of chemotherapy with CDDP (75 mg/m 2) and 5-FU (1000 mg/m 2) at the first … (15) The insulin-induced activation of the Na+-K+ pump leads to decreased intracellular Na+ concentration and hyperpolarization, but none of these events can account for the concomitant activation of the glucose transport system. Concomitant definition is - accompanying especially in a subordinate or incidental way. XARELTO should not be used in patients with creatinine clearance (CrCl) 15 to <80 mL/min who are receiving concomitant combined P-gp and moderate CYP3A inhibitors unless the potential benefit justifies the potential risk. What year will may 22nd fall on Tuesday right after 2007? Concomitant radiochemotherapy, as compared with sequential radiochemotherapy, improved survival of patients with locally advanced NSCLC, primarily because of a better locoregional control, but at the cost of manageable increased acute esophageal toxicity. [from early 17th c.]quotations ▼ 1. Who is the longest reigning WWE Champion of all time? A suspect drug is a drug which is thought to be associated with the adverse event in question. of coinciding at the same time, while concomitant has more focus on Concomitant Administration of Proton Pump Inhibitors and Capecitabine is Associated With Increased Recurrence Risk in Early Stage Colorectal Cancer Patients Clin Colorectal Cancer . (17) Ketazolam was found to be significantly better than placebo in alleviating anxiety and its concomitant symptomatology as measured by the Hamilton Anxiety Rating Scale, three Physician's Global Impressions, two Patient's Global Impressions, and three Target Symptoms. language I use concomitant for medication used at the same time, Documenting Concomitant Medications in Clinical Trials By S. Eric Ceh A concomitant medication (con-med) is a drug or biological product, other than a study drug, taken by a subject during a clinical trial. See more. (13) Rats were divided into four groups: drug naive controls; HAL-treated for 6 months; AMPH-treated for 1 month; and rats administered both continuous HAL for 6 months and concurrent AMPH treatment during the 2nd month of HAL administration. All concurrent sporadic AMLs were benign. Epub 2011 Sep 8. concomitant (not comparable) 1. They are often used interchangably. (18) It is concluded that there is no pharmacokinetic indiction for withholding OCs from women with early active schistosomiasis who are concurrently receiving antischistosmal drugs. (10) In the present work, we measured the inactivation of methionine synthase and the concurrent homocysteine export rate of two murine and four human cell lines during nitrous oxide exposure. Concomitant drugs are two or more drugs used or given at or almost at the same time (one after the other, on the same day, etc.). As adjectives the difference between concomitant and coadministered is that concomitant is accompanying; conjoined; attending; concurrent while coadministered is administered along with another material. Sequential vs. concurrent chemoradiation for stage III non-small cell lung cancer: randomized phase III trial RTOG 9410 J Natl Cancer Inst. What is the difference between concomitant and concurrent radiation therapy. They are often used interchangably. (12) This preliminary study estimates the occurrence of concurrent helminth infection in Africa and Brazil to determine whether such an approach is justified epidemiologically. (16) In 1 patient there was concomitant aneurysmal dilatation of the brachiocephalic trunk. “Interesting study, but underpowered to adequately compare sequential vs concomitant treatment,” he told Cancer Network. Why don't libraries smell like bookstores? What is exact weight of male Bengal tiger? (a.) Carboplatin plus 5-fluorouracil (carbo-5FU) is another accepted treatment option with a different toxicity profile. As an adjective, concurrent means running together in space, as parallel lines; going on side by side, as proceedings; occurring together, as events or circumstances; as well as covering the same ground; having authority or … (5) It reduced serum AP levels, increased serum Ca levels, increased bone ash weight, epiphyseal and metaphyseal bone volume, with a concomitant reduction in epiphyseal and metaphyseal bone marrow volume. Concurrent sentences. As a noun concomitant is … Copyright © 2021 Multiply Media, LLC. What is the kannada word for quinova seeds? Hakim A(1)(2), Ghoshal S(1), Verma R(3), Sharma SC(1). Acting in conjunction; agreeing in the same act or opinion; contributing to the same event or effect; coöperating. (3) Focusing on two prospective payment systems that operated concurrently in New Jersey, this study employs the hospital department as the unit of analysis and compares the effects of the all-payer DRG system with those of the SHARE program on hospitals. concomitant synonyms, concomitant pronunciation, concomitant translation, English dictionary definition of concomitant. * (John Locke) It has pleased our wise Creator to annex to several objects, as also to several of our thoughts, a concomitant pleasure. Section 22-Payment Concurrent with Delivery.. Concurrent with that should be deity worship.. Concurrent with the publication of these reports, a public forum will be opened.. Concurrent with these improvements, total maintenance costs were reduced by 12%.. The majority of patients with concomitant AML and RCN were female (78%). A concomitant drug is a drug which the patient is using at the time of the adverse event in question. Concurrent (adjective). Define concomitant. (n.) One who, or that which, concurs; a joint or contributory cause. (16) A more specific differentiation, as indicated by the sharp increase in GAD levels which was concurrent with an increase in interneuronal contacts, lagged behind the initial growth. (14) Insulin treatment (1 unit.kg bw-1.hr-1) prevented a further increase of the plasma free fatty acid level, observed concomitantly in the control group. What does contingent mean in real estate? Author information: (1)1Department of Radiation Oncology, PGIMER, Chandigarh, India. There was a trend towards better OS (87.2% vs. 78.6%) in study arm than the control arm, although it was not statistically significant, probably due to relatively small sample size. The protocol normally defines a specific reporting period in which the subject’s use of con-meds is documented, e.g., from 60 days Is there a way to search all eBay sites for different countries at once? If you want to nuance the DICTIONARY.COM The term has two contextual uses: as used in medicine or as used in drug abuse Concomitant drugs in medicine. Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. Concomitant use of warfarin and ticagrelor as an alternative to triple antithrombotic therapy after an acute coronary syndrome Thromb Res. How to use concomitant in a sentence. Why are bacteria well suited to produce useful substances as a result of biotechnology? What is the distrbution of water in the lithosphere? (2) The highest rate of discontinuation occurred when method choice was denied in the presence of husband-wife agreement on method choice, and the lowest rate occurred when method choice was granted in the presence of such concurrence. This designation is used when medicinal drugs are given either at the same time or almost at the same time Concurrent and Consecutive Sentences. popular alternative Nearby Words: concurrence, concurring, concurrently, concurrency 1 A post-hoc analysis examined patients on XARELTO and warfarin based on the use of non-dihydropyridine calcium channel blockers (CCBs) at baseline in the … (a.) Conjoined; associate; concomitant; existing or happening at the same time. @medica well put. How old was Ralph macchio in the first Karate Kid? (20) Enzyme levels in strains with concurrent mutations in both regulatory genes are considerably higher than the sum of the levels in strains with a cytR or a deoR mutation alone, indicating a certain co-operativity between the two repressor proteins. (10) The concomitant reduction in aortic pressure and increase in heart rate following total occlusion of the portal vein were most pronounced during the first weeks after stenosis, and were probably due to diminished venous return to the heart. (8) It is clear that before general release of a new living feline infectious enteritis vaccine, there must be satisfactory evidence that concurrent infection will not affect the safety of the modified antigen.In cats infected with feline infectious enteritis there appears to be a short period, coinciding with the onset of leucopaenia, during which they are highly infectious. 1970, Alvin Toffler, Future Shock, Bantam Books, pg. Adjective (-) Accompanying; conjoined; attending; concurrent. A concomitant drug won’t have any relation with the adverse event. Conjoined; associate; concomitant; existing or happening at the same time. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. (2) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis. (19) The development of renal insufficiency during enalapril therapy may be exacerbated by concomitant diuretic therapy and should raise the suspicion of underlying transplant renal-artery stenosis. How old was queen elizabeth 2 when she became queen? What was lasik visons competitive priority? What is the WPS button on a wireless router? (3) The individual classes of drugs are first treated separately to highlight specific aspects of their quantification, and this is followed by an overview of those methods permitting the concomitant analysis of two or more antiepileptic compounds. (6) Both demonstrated concurrent validity and feasibility. – Mark Bao Jan 18 '15 at 7:38 During concomitant temozolomide therapy, grade 3 or 4 neutropenia was documented in 12 patients (4 percent), and grade 3 or 4 thrombocytopenia occurred in 9 patients (3 percent) . my work, I use "concurrent diseases". “Clinicians will continue to give concomitant treatment on the basis of other studies suggesting better efficacy and to enable treatment to be completed sooner.” When sentences run consecutively, defendants have to finish serving the sentence for one offense before they start serving the sentence for any other offense. Concomitant definition: Concomitant is used to describe something that happens at the same time as another thing... | Meaning, pronunciation, translations and examples 2011 Oct 5;103(19):1452-60. doi: 10.1093/jnci/djr325. accompanying with a sense of lesser importance. (n.) One pursuing the same course, or seeking the same objects; hence, a rival; an opponent. What is the difference between concomitant and concurrent radiation therapy? Presumably she's looking to make a point, concurrent with her 15 minutes of fame. (7) In the first experiment ovariectomized female hamsters were administered varying dosages of progesterone (P), dihydrotestosterone (DHT) or CI-628 at the same time (concurrently) as estrogen (EB) or 48 hr after EB (sequentially). (12) Fourteen patients with symptoms or with high-grade carotid artery occlusive disease were treated by concomitant carotid endarterectomy. (17) Concurrently, stereology was applied to quantitate: (1) the density of RNA labelling, and (2) changes in the size of the nucleus and nucleolus in response to estrogen treatment. We aimed to compare the efficacy and safety of different concurrent chemotherapy regimens in the context. (4) In fact, the addition of conditioned medium obtained by 48 hr preincubation of isolated monocytes with 10% PF-382 supernatant (M-CM2) or the concomitant addition of supernatant from PF-382 cells (PF-382-CM) and from unstimulated monocytes (M-CM1) are capable of fully replacing the presence of monocytes in the BFU-E assay. John Locke 2. I think that meaning is close to what I get from concomitant, which is (as you say) slightly different than associated. (adsbygoogle = window.adsbygoogle || []).push({}); (n.) One who, or that which, accompanies, or is collaterally connected with another; a companion; an associate; an accompaniment. 2015 Jan ... Ticagrelor is a more potent platelet inhibitor, but data supporting concurrent use of ticagrelor and warfarin (dual antithrombotic therapy, DT) is limited. What date do new members of congress take office? All Rights Reserved. Section 15-Delivery Concurrent with Payment.. (9) Concurrent with this change in the level of enforcement of RBT was an extensive publicity campaign, which warned drinking drivers of their increased risk of detection by RBT units. The mean age of patients with concomitant AML and RCN was higher than the mean age of patients with only AML (58.6 vs 55.5 years). Acting in conjunction; agreeing in the same act or opinion; contributing to the same event or effect; cooperating. Clear-cell renal cell carcinoma (RCC) was the most common malignancy associated with AML (56%). (5) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase. (13) It is concluded that in this cell type (i) somatostatin-14 is exclusively generated by dibasic cleavage at the Arg-2-Lys-1 site of the intact precursor with concomitant production of prosomatostatin[1-76], and (ii) no direct interactions between the monobasic and dibasic processing domains occur. How long will the footprints on the moon last? From my sense of For medical conditions that are present today but not the focus of (11) This indicates a potential use for 1,25(OH)2D3 to prevent and treat hypocalcaemic cows with or without concurrent hypomagnesaemia. Background: Chemoradiotherapy (CRT) including three cycles of cisplatin is considered the standard of care for locally advanced head and neck squamous cell carcinoma (LA-HNSCC). (n.) One of the supernumerary days of the year over fifty-two complete weeks; -- so called because they concur with the solar cycle, the course of which they follow. (15) However, MPA did not enhance survival when given concurrently with radiotherapy; indeed, at the higher of these two doses, median survival of tumor-bearers was slightly less than with radiotherapy alone. Concomitant definition, existing or occurring with something else, often in a lesser way; accompanying; concurrent: an event and its concomitant circumstances. Concurrent can function as both an adjective and a noun. difference, concurrent has a bit more focus on the temporal aspect (14) Inhibition of RNA synthesis by MTX was prevented by concurrent administration of HX. Consecutive refers to things that are arranged or … What chores do children have at San Jose? (18) Concomitant with the inhibition of K+ and Na+ transport, quinine stimulates ATP hydrolysis by 57%. As a noun concomitant is something happening or existing at the same time. The material on this site can not be reproduced, distributed, transmitted, cached or otherwise used, except with prior written permission of Multiply. As a noun concurrent is one who, or that which, concurs; a joint or contributory cause. Summary. Occurring or existing concurrently; attendant: poverty and its concomitant social problems. (20) The age of the patient at onset of surgical and concomitant conservative therapy determined slight differences in kinetics but not in degree of compensatory growth. (4) Although each of palate and limb is concurrently susceptible to epigenetic regulation, their differential intrinsic genomic capabilities appear to have been uncoupled. Comparison of Functional Organ Preservation by Concomitant Boost Radiotherapy Versus Concurrent Chemoradiation in Locally Advanced Carcinoma of Larynx or Hypopharynx: A Prospective Randomized Study. 4.3K views (a.) (6) This transient paresis was accompanied by a dramatic fall in the MFCV concomitant with a shift of the power spectrum to the lower frequencies. (9) Concurrent with this change in the level of enforcement of RBT was an extensive publicity campaign, which warned drinking drivers of their increased risk of detection by RBT units.
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